Wow! What a thread.
If you are shooting only one type of subject, say studio portraits, and have lots of experience, then it only makes sense for you to do whatever works for you.
If what you are doing isn't working well, try something else.
In any case,
keep in mind that we are working with machines that can, and sometimes will, get it wrong. We always have to think through what we are doing.
To the extent that the shot is unusual (to us) or extra important, bracketing might be the saving factor. An "ugly" solution perhaps, and models might object. Landscapes never object, but lighting on landscapes can be variable (always changing, slowly or quickly) so experience and intelligence are big helps.
For landscapes, I prefer to set exposure to manual, compose a frame that the camera's metering system will have minimal trouble with, set the exposure, then recompose and shoot. For flash, the only good way (with my limited abilities) is to go for aperture priority, shoot, look at the results, and dial in compensation if needed. In extreme situations I bracket. Shooting RAW helps me - for example when shooting fireworks I have no way to know in advance how bright the next shell will be.
So, to contribute a little to the OP's questions:
1. To go with whichever works for me in the situation at hand. There is no one way that works best in all cases.
3. Yes, there are. If you use TTL the results may be skewed by composition/aiming; you are at the mercy of what the camera "thinks" about the scene/target; you may be helped, or you may suffer; you still have to think through "how much exposure comp do I need to adjust for the camera's assumptions about reflectivity, and scene type (if using matrix).
How many of you out there prefer using a handheld meter versus TTL metering in your camera? I have a D700 and have been reading pros and cons to both but would like to hear forum participants on this issue.
1. When would you use one over the other?
2. Why?
3. Are there any specific negatives to using TTL in the D700 over a handheld metering system?
Thanks for your responses!