There is an often repeated declaration that high ISO reduces noise. This is caused by the signal processing when the sensor image is processed and conditioned for the ADC. Although the reduction does happen, I have never seen this to be visually significant. You can infer this in D Cox thread a week ago
With his SNR test using Photoshop to indicate the STD deviation of the test patches. Indeed a small improvement of SNR above ISO 1270 does happen.
I don't know for sure why he got the results he did, but his test was done very crudely, and probably wrong. I don't see how he could have made valid measurements the way he did it. We didn't see his raw data or his images, so it's hard to know exactly what he got or what he should have measured. For his camera there should not be much difference above ISO 1600.
I don't know for sure why he measured low values at low ISO, but he measured DN values
on jpeg files, and I suspect that he made a mistake. He varied the ISO setting by a factor of 256. That's 8 stops, and that may cause serious numerical errors. I think it's possible that he clipped the low-ISO values, and in so doing, destroyed the record of noise. Alternatively, his method of exposure correction could have altered the numbers in a non-proportional way. The patches he measured may have looked noise free, but the method seems error-prone, and I'm not sure he actually measured noise with sufficient accuracy.
I don't want to discuss those further because the data is completely inadequate to say anything definitive. To put it bluntly, I don't believe his results.
EDIT: I still don't know what's wrong, but it's not credible that he gets lower noise by exposing for ISO 25600 but setting the ISO at 100. For his camera, saturation at ISO 25600 is 293 electrons and read noise is 0.611 electrons. At ISO 100, read noise is 6.77 electrons. At ISO 25600, S/N - 480 at most; at ISO 100 S/N is 43 at most, just considering read noise. Shot noise and fixed pattern noise are constant, so there is no way for total noise to be lower for ISO under the stated test conditions. There is way too much room for error in his methods, in my opinion.
EDIT 2: Under more realistic conditions, let's expose 1 step down to give some headroom, then expose a dark part of the image, another 5 steps down, instead of pure white. Then, considering read noise only, the S/N ratios would be 7.5 and 0.67 for ISO 25600 and 100, respectively. That picture would look horrible.
I shot Canon 1D and 5D series extensively for low light performing arts between iso 3200 and ISO 12800 but have never seen a significant improvement of SNR.
That's to be expected.
For your cameras the difference in read noise between ISO 3200 and 51200 is quite small. The difference between ISO 3200 and 100, on the other hand, is quite large.
It's worth making two other comments. First, read noise is only one source of noise, and it's usually visible only in the deep shadows. At higher exposures, shot noise (photon statistical noise) usually dominates. Second, be careful about expressing noise in units of digital numbers (DN). If you try to compare noise measured at ISO 100 with noised measured at ISO 200,
be aware that the numbers you read in the files are usually not comparable at any two ISO values, because of some combination (1) a different voltage for each ISO value; (2) multiplication by a different scale factor; or (3) a different capacitor in the circuit. To get around this problem, signal and noise in the sensors are measured in actual physical units, namely electrons.
If you do the comparison correctly, many camera sensors
do show significantly more read noise at low ISO values. Whether you will see the difference is another matter altogether. It just depends on the signal and noise levels. With modern cameras, read noise is tending to become insignificant in many cases.
A number of years ago when this was first discussed, I did the appropriate test and, with pixel peeping, the noise reduction does exist but not to any degree to be of an advantage when shooting theatre or dance.
It would be nice to see a practical example of the noise reduction for real world shooting.
Am I misunderstanding or missing a salient point ?
Maybe. Whether you can see the read noise depends on the camera, the exposure, and the brightness of the print.