I've uncovered some additional funkiness.
I'm having trouble getting Photoshop (26.2.0) to run in 30 bit mode, unless automatic color management is enabled.
If I set the Registry keys to zero, toggling the nVidia color setting in the control panel set them back to 1.
What I saw when I mentioned this previously:
"I did notice an oddity today; I set one of the desktop's Windows installs to allow 120Hz and 10-bit color, after selecting "Use NVIDIA color settings." in the Nvidia Control Panel.
When I went back to the Color Management page, it had set the ACM to "On", so I had to disable it again."
Except rather than the Registry setting, I saw the change on the CM page.
I was relaxing on a laptop this evening, but I just got curious and fired up the same desktop Windows install I was using this afternoon; "Nvidia color settings" is still selected, and the new Nvidia control panel settings of 120Hz and 10-bit are preserved even after ACM was disabled on the Windows Settings CM page. The Registry also has ACMEnable set to "0".
If anything is wrong, I haven't detected it yet. I don't use Photoshop, so can't check that. And I'll be careful not to toggle "Nvidia color settings" so as not to risk breaking something.
I wish I understood this.
So do I. There's things going on behind the scenes that I don't see a reason for.