I did a simple test to find out whether I'd stay with Topaz Sharpen AI $or renew my Topaz Photo AI licence (and upgrade from v3.2.2 to v3.3.3), because there's one thing that's been bothering me: from Lr, Photo AI opens the RAW file (i.e. without any post-processing) whereas Sharpen AI creates a TIFF file before editing. So I was wondering how Photo AI would handle an underexposed subject in a backlit photo?
By chance I had the perfect photo, including moving blur, for this test :

RAW file imported in Lr
In Lr, I can simply post-treat that way:

After a simple post-treatment in Lr
Then with Sharpen AI I get this result, which I found really acceptable :
[ATTACH alt="Sharpening with Topaz Sharpen AI in "Motion Blur - Very Noisy" mode"]3532158[/ATTACH]
Sharpening with Topaz Sharpen AI in "Motion Blur - Very Noisy" mode
A little zoom shows clearly the improvements in terms of sharpening while managing the noise :

Sharpening comparison with Topaz Sharpen AI
Now if I use Autopilot in Topas Photo AI, here is what I get !

From Lr to Topaz Photo AI with AutoPilot and Lightning on Subject only
So, clearly this is a complete another story ! Not only does Topaz Photo AI fail to manage lightning correctly, it also adds white aberrations around the edges, a sign of poor lighting management, which is clearly visible when the lighting is turned up to maximum intensity.

From Lr to Topaz Photo AI with AutoPilot
Conclusion : as far as I'm concerned, this version of Topaz Photo AI is aimed at the general public, who aren't very demanding. So before giving any more $$ to TopazLabs, I'm going to wait for a more advanced version that really lets you get convincing results simply, while leaving you the freedom to adjust the settings more finely.
So, as you can see, it's not worth it for me at the moment, even though (and I still don't understand why, as it worked without a hitch before) my version of Topaz Sharpen AI has been having problems with flickering on the screen since the last update to 4.1.0