I will be curious to learn how the Z8 does in low light / high ISO situations (as compared to the Z6II and Z7II) ? Although the Z7II was close - I still perceived the Z6II as being better in producing the cleanest low light / High ISO images ... Perhaps with the newer Z8 we might see improvement over the Z7II for low light / high ISO images which produce less noise and cleaner images equal to or better than the Z6II produces in low light / high ISO situations ?
How well the Z8 (and the Z9) does depends.
1) What do you mean by high ISO? For some it’s anything over 500. For others it’s over 2000, others it’s 6400. For some it’s 12,000.
2) How well can you fill the frame and avoid cropping at those levels?
3) How much fine detail do you need or expect and how much pixel peeping do you do?
How well the Z9 does in the ISO 800 to 6400 + range for me depends a great deal on how much cropping I have to do and how much fine detail I need or expect to retain. I can shoot full frame and even DX crops of people at ISO 2000 and not have to use post processing noise reduction software even after lifting the shadows or exposure of the subject. But I’ve also seen noticeable noise when cropping in and pixel peeping feathers of small birds at ISO 800.
So it all depends. Also, I guarantee you the person shooting in low light with a 400 f/2.8 will enjoy the sensor more than the one shooting at 400 f5.6, or at 85 mm and f/1.8 vs f/4, just as the one shooting at 800 f/6.3 will be better off than the one shooting at 400 f/6.3 and cropping in. I bet higher megapixel sensors sell more of the more expensive glass options than any marketing print because the higher megapixel sensors benefit more from the better glass.