The DOF is being made into a bigger issue than it really is. Yes there is a difference, and yes at f/1.4 on a 35 or 55 FF you will get smaller DOF. But if you're already happy with the DOF you get on your current cam, then you'll have no regrets with the x-pro 1 or any other APS-C. I wouldn't be too concerned with that facet of your decision, just consider it when making the choice.
Price..they seem comparable. Draw. Besides, we all know that if we REALLy want one over the other, and the price is close, we'll find a way to buy it, won't we?
Lens choice is a real issue. But, the message that Fuji sent is that they're committed, and they've explicitly laid out a roadmap of lenses. They look fairly comprehensive on paper, and certainly would satisfy your demands based on your stated usage.
Focus, performance, etc - there's no way to know. These forums are rife with confident predictions and preemptive decisions on whether to get one or not, all based on (sometimes very well thought out) conjecture. None of us know how it will perform. So the risk is there. You have time, just wait till it comes out and then decide, no?
Based on what we DO know, there are pros/cons for both. Size, easy, the fuji wins. Trust me, even with an APS-C DSLR, you're gonna not want to have to lug it around all day. The DSLR is also more bulgy and awkard when carrying it. It's one of the reasons those who love rangefinders love them. The fuji is not "small" in that p&s sense of the word, but my guess is you'd love carrying it around more than a DSLR. Also, as someone mentioned, dynamic range is prob gonna be a lot better. DR was never BAD on the 5D's, but there is a very (to me, and many many people) discernible difference in DR and what that allows you to do, with the newest (SONY) sensors. If this sensor is anything like those, you'll be very very happy.
It's very likely you won't, generally, get the speed and responsiveness with the fuji that you will with the 5D (or any DSLR). You are trading size and shape for performance. Doesn't mean that's not something worth trading, depending upon what you're after.
I don't think the FF v APS-C would be that big of a turning issue for you if you had both systems in your grubby hands this very second, an spent a month with them both. I think you'd decide based on how good it felt to use each (size, shape, weight, look, feel, and of course image quality and response). Either one is (likely) going to take terrific photos.
The End