Carl, the question is are you willing to pay twice the price for 10 or 20 % better autofocus speed and tracking ability ?
For most non-pros the answer is save your money. Sigma lenses are pretty good for the price.
But, are you willing to spend a lot of money to get every last bit of performance out of your camera ? In that case, buy Nikon.
I started out with the Sigma 24-70 2.8 and Sigma 70-200 2.8 after using my Nikon 24-120 for 6 months. They were OK, but when I could afford the Nikon 70-200 VR I didn't look back.
(I DID like the smaller size of the Sigma 70-200, and it's zoom ring was so easy to turn that I could zoom by just balancing the lens on my fingertip, but I don't think that lens was equal to the Nikon wide open - I could be wrong.)
I bought the Bigma (Sigma 50-500) TWICE and returned it both times because the focus speed and ability to track focus was just NOT up the the standard of the 70-200 with 1.7 x teleconverter attached. I wanted more zoom but the Bigma could just not keep up with my fast little dogs. I thought my first unhappiness with focus speed was because of my D70, but when I tried the lens again with my D2X I was just as unhappy with it.
I looked at the Sigma 120-300 for a while, but I'm pretty sure the zoom ring on that lens spins in the OPPOSITE direction compared to all Nikon lenses - and there is no way I could get accustomed to using that instictively when sometimes using the Nikon 70-200.
I could finally afford the $8,000 Nikon 200-400 f4 lens and I don't even touch my Nikon 70-200 any more. I love the 7 pound monster.
I don't think I will ever buy a non-Nikon lens again, but then again, I am willing to spend several thousand dollars more for just a small improvement in performance.
--
Bill,
http://www.pbase.com/billmcintyre