I tried Neat Image but although I tried various settings I found that it tended to slightly blur the whole image while removing noise. It seems there is a compromise to find between noise and blur and I found photoshop intereting to this respect because it allows you to accurately select the area of the image in which noise has to be removed. This way you only blur the selected area and not the whole image.However in camera noise reduction is applied to every shot in the
same way. Using NeatImage you can tune the NR specifically for the
image. This means you can eliminate noise AND retain detail AND
sharpen at the same time. However its tough to use for images
without a fairly large area (60+ pixels square) of a single colour
and it can take a LONG TIME to get right on some pictures and build
up a decent library of profiles.
maflu