I used to use the serial port and had trouble. If connection seemed to fail I had to come out of Picturegear, have the camera on and get back into Picturegear. However, using the top menu bar and the drop down menu for connecting was a lot more reliable than using the menu on the left of the screen.
Better still, get Win 98 and use the USB connector. Of course you'l need a USB input on the PC! It is very much faster. There are other connections available but I have not used them. Almost anything is better than a serial connection.
At this moment Sony have not made software available for Win 2000.
Sandy