Looking at your previous posts you were shooting with C 28-135 IS and the 17-40 L.
First...the Tamon 18-250 or any superzoom is simply no match to these lenses. To get comparable quality, try the DA17-70, DA55-300, the Star or the Limiteds.
If you insist on using the Tamron 18-250, set your aperture to F/8 or darker - of course you'll need to up the ISO to 400 and maybe use SR or a tripod, too.
Then, I assume you've already tried Bright mode for JPG. My setting is Bright, Sharpness+1, Saturation-1, Contrast unchanged - this combination gives me pictures with sharpness that I like.
More, since you came from the C 10D, you may find the 100% crop performance not comparable at all - especially if you're using a superzoom on a 10MP sensor, comparing with L lenses on a 6MP sensor. For a fair comparison, reduce your K10D picture to 6MP.
If doing these still don't give you sharp pics with the details that you want, then maybe you have a FF/BF problem. Try using manual focus and see if the camera has FF/BF - if so send the combo to Pentax to correct it.
C bodies have a tendency to correct less on Tungsten WB. If you find the Tungsten WB on Pentax too blue, you can fine tune it to give it more yellow/red. As far as I can remember, fine tuning WB was not possible at all on a Can*n 10D.
I'd been using a Canon 10d prior to buying a Pentax 10D along with a
Tamron 18-250 zoom. I wanted a single very long range zoom to use
for travel, and there was nothing appropriate with image
stabilization at the time for the Canon. I don't shoot RAW on either
camera and don't do a lot of post-processing. Comparing photos taken
with the two cameras, though, the Pentax are soft, lacking in
sharpness and detail. Another thing that troubles me is that when I
set white balance to "Incandescant" on the Pentax, I often get very
blue, unnatural looking color; not so on the Canon. Anyone have any
ideas? Appreciate any help. Thanks.