Post processing workflow
It's well worth watching the thorough video tutorials on the Topaz site. They're very informative and well produced. DeNoise works well enough on default, but really gets amazing if you disable NR and dial down the black point setting in your RAW converter (i.e. open up the shadows), process in DeNoise, and then set the black point to get your blacks back after returning to your image editor.
'No matter where you go, there you are.'