Intuos 5 workflow with Lightroom 4?
Brush adjustments... that's about all I can think of though of course you can use the device as a mouse replacement in general.
It shines in Photoshop for sure.. LR - I wouldn't think it's all that much better than a mouse though.
Agreed. Even the brushes in LR are fairly imprecise - if I need anything that requires masking or careful brush application I will edit in PS, not LR. I only ever touch my tablet in PS.