Fuji x-E1 Color Bleeding Locked

I've had this issue on my X100 photos when put through Lightroom 3.6 too, although not so often. Funny thing is, the images will look absolutely fine if I just work with the exposure and develop tools but if I then adjust the angle of the horizon using the crop tool the image immediately looks like a watercolour ! I've used Lightroom since the first version with a few different cameras but have never known anything like the problems I sometimes randomly get with the Fuji. If it were a consistent problem I'd look for another solution but it isn't, which is the most annoying thing as Lightroom is the most intuitive bit of photo processing software I've used