Software instead of tilt-shift lens?

No one has mentioned Lightroom 4's "Vertical" slider.  It's fast and easy and for most situations works very well.  I usually find a vertical line near the center of the picture and align it perfectly as a good starting point, then I work the "Vertical" slider from there. In the Develop Module, under Lens Correction, click on Manual and you'll see it.  You can also "Rotate" the image from this panel and work with distortion.  There's a Horizontal slider for when you're not perfectly positioned to line up a head on shot and want things to look a little better, but I seldom use this.

In PS, at least the older versions, I'd have to use a Transform tool, then pull the corners of the picture out individually.  The LR4 slider is much more convenient and I wouldn't be surprised it's also in LR4's bigger brother, CS 6.

--
Enjoying God and His Creation.