Some query about DxO Optics Pro
DxO can't do any edits to the RAW file itself.
I haven't used lightroom, but maybe you would get most of the functionality by exporting as 16 bit TIFFs and editing those in lightroom.
EDIT: If you go with the TIFF:s, you probably want to minimize all alterations by DxO. Disabling "DxO Lightning - HDR" is the most important thing. (Probably the only thing that matters). You can then save the new preset from the drop down menu "presets" with "create a new preset", so you can easily apply it to all photos. You can even make it default from preferences.