backpack with slr spot, not slr backpack?

Have you considered any of the booq bags? I have the boa flow XL. It is a backpack with a pouch at the bottom that (in my case) holds a D300s with grip and a 50mm 1.4 lens. The rest of the bag then comfortably fits an 18-200, 70-300, SB900, a laptop, jumper/jacket, filters, ipods, kindles, etc. etc. There are other models that are a bit smaller, but they all seem to follow the bag with space for a camera in it theme.
RP