Yes. I've used MIS ink
for over 5 years now in two printers Canon iP4000R (dye) and an Epson R2400 (pigment) . I have had no issues at all !! Their ink has not block nozzles or caused any sort of printer failure. Good quality third party ink is perfectly safe. I make my own ICC profiles and comparing OEM with MIS inks cannot see any difference. What ever ink you go for get your ink/paper combo profiled if you can its well worth the effort.